Alpha Beta Arteether
Manufacturer & Exporter of Alpha Beta ArteetherMonograph number:
853
Title:
Alpha Beta Arteether
Specification
IHS (In House Specification)
Category
Antimalarial
DMF Status
TP (Technical Package)
CAS Registry number:
[75887-54-6]
CAS name(s):
[3 R- (3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12a R* )]-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12 H- pyrano[4,3- j ]-1,2-benzodioxepin
Additional name(s):
dihydroartemisinin ethyl ether; dihydroqinghaosu ethyl ether
Drug code(s):
SM- 227
Molecular formula:
C 17 H 28 O 5
Molecular weight:
312.41
Percent Composition:
C 65.36%, H 9.03%, O 25.61%
Literature references:
De rivative of artemisinin, q.v. Prepn: Y. Li et al., Acta Pharm. Sinica 16, 429 (1981). Synthesis and antimalarial activity: China Cooperative Research Group on Qinghaosu, J. Tradit. Chi nese Med. 2, 9 (1982); A. Brossi et al., J. Med. Chem. 31, 645 (1988).
Properties:
White crystalline solid, mp 80-82degrees . [alpha] D 21 154.5degrees (c = 1.0 in CHCl 3 )
Melting Point:
80-82
Rotation:
154.5
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